Puerarin could directly benefit DM by decreasing blood glucose level, improving insulin resistance, protecting islets, inhibiting inflammation, decreasing oxidative stress, and inhibiting Maillard reaction and advanced glycation end products (AGEs) formation.
Maitake mushroom consumption has been proven to help reduce blood glucose level in rats with Type II diabetes. Due to the high similarity between rat and human genome sequences, it is promising that eating maitake mushrooms might also be good for patients with Type II diabetes.
Chromium enhances insulin function, and low chromium levels are thus associated with many blood glucose metabolic issues, such as sugar cravings, insulin resistance, metabolic syndrome, glucose intolerance, type II diabetes, elevated cholesterol, atherosclerosis, and overweight.
Mulberry leaf possesses various beneficial effects against cardio-metabolic risks, including anti-hyperglycaemic, anti-hyperlipidemic, anti-obesity, anti-hypertensive, anti-oxidative, anti-inflammatory, anti-atherosclerotic, and cardio-protective effects.